Videos

Every 3 minutes, a woman dies of ovarian cancer somewhere in the world. "Ovarian cancer is very sneaky. Most of the patients respond positively to the therapies initially provided to them, but eventually, the cancer comes back and is much more aggressive. As a result one in two ovarian cancer patients die within 5 years after diagnosis." But what if we were able to treat ovarian cancer with a new therapy using our cells?

What if there might be a way to tackle the side effects of cancer treatments, such as fatigue, chronic pain and anxiety, even before the treatment begins? Kenza Mostaqim (VUB) introduces you to 'prehabilitation'.

Why do people get cancer, arthritis, or Alzheimer's? Essentially because a protein key in our body does not fit in its respective lock. This is why Alvaro Martin is looking at removing defective keys and designing new protein keys. Keys that fit and can open the necessary locks, so that for example, our immune cells target and kill cancerous cells. "Protein design can be the key to unlocking a future without diseases."

Up to 25% of the cells present in lung cancer tumours are currently ignored. As such, we don't know what the role of these so-called B cells is. "It is crucial to figure that out because we cannot efficiently fight something we do not fully understand," says Pauline Bardet (VUB - VIB - FWO).

In her PhD, she wants to get to the bottom of those B cells and thus find out whether those cells are "good guys" or "bad guys".

Once diagnosed with glioblastoma, a highly aggressive brain cancer, a patient has on average only 15 months to live. "This terrible statistic shows that we urgently need new treatment options," says Myrthe Mampay (VUB - FWO). In her research, she is looking for one such new treatment based on immunotherapy, in which she wants to use patient stem cells to make macrophages that attack the tumour.

In the last decade, wildfires peaked at record numbers in different countries across the world. These fires destroy houses and burn down forests, but they also have other important 'unseen' effects. "Smoke from wildfires leads to high air pollution, which is associated with short and long-term risks, such as respiratory and cardiac diseases", as Leonidas Leiva explains. He's working on new materials to recognize, capture and neutralize these contaminants.

Over the past five years, solid progress has been made in the fight against cancer, but unfortunately, that does not apply to pancreatic cancer. So what makes this cancer so hard to beat? Olaya Lara (VUB) explains this by comparing it to a football match. She also tells you what tactics she figures out to sideline xCT, the Lionel Messi in the pancreatic cancer team. 

The fight against breast cancer does not stop with overcoming cancer. 1 in 3 women continue to experience pain symptoms even during a harmless activity such as cycling. Physiotherapist Eva Roose (VUB) wants to help these breast cancer survivors reset their pain alarms.

Why do cancer patients relapse despite receiving treatment? This is often due to dormant cancer cells. These cells lie dormant in the body and manage to escape treatment, for example, chemotherapy. Can substances from camel and llama blood provide a breakthrough?

Did you know that cancer cells are not so different from our healthy cells? This makes it difficult for T-cells, important immune cells in our body, to recognise and fight cancer cells. Cancer researcher Heleen Hanssens (VUB-FWO) wants to give T-cells a helping hand by equipping them with more sensitive receptors, or antennae, that are pre-programmed to unmask cancer cells. In the lab, she is looking for the perfect form for these CAR antennae, so that they become more stable and better at detecting cancer cells. 

With the current corona pandemic, viruses are seen as more dangerous than ever. But did you know that some viruses can help us fight cancer? Jolien De Munck is studying the potential of these so-called 'oncolytic viruses'.

Joeri Lambrecht (VUB - Vrije Universiteit Brussel) developed a simple blood test that allows for a faster, safer and cheaper detection of liver fibrosis.