Videos

Why do people get cancer, arthritis, or Alzheimer's? Essentially because a protein key in our body does not fit in its respective lock. This is why Alvaro Martin is looking at removing defective keys and designing new protein keys. Keys that fit and can open the necessary locks, so that for example, our immune cells target and kill cancerous cells. "Protein design can be the key to unlocking a future without diseases."

Thanks to advanced proton therapy, doctors can precisely start irradiating brain tumours. Unfortunately, they do not yet dare to use this technique on tumours in the belly. Why? Because it's a bit like playing darts with a blindfold, while you have to hit a moving target, as Sophie Heymans explains in this video. She tells you about the technique she is working on to help doctors face this challenge.

Rats are our best friends. Or at least Emilie Bartsoen's. She only has to listen to her rats to know how they feel. By observing the social behaviour of rats, she also wants to help people with autism. How? She explains that to you in this video!

Do you ever wake up feeling like you have been run over by a truck? You are not alone. As many as 1 in 5 adults suffer from a sleep disorder, ranging from sleep apnoea to insomnia. With a compact, wearable device and AI, Elisabeth Heremans wants to analyse sleep problems in patients from the comfort of their own bed, instead of having them spend the night in a sleep clinic attached to a bunch of wires.

Up to 25% of the cells present in lung cancer tumours are currently ignored. As such, we don't know what the role of these so-called B cells is. "It is crucial to figure that out because we cannot efficiently fight something we do not fully understand," says Pauline Bardet (VUB - VIB - FWO).

In her PhD, she wants to get to the bottom of those B cells and thus find out whether those cells are "good guys" or "bad guys".

Roughly every 5 minutes someone on this planet dies of ALS, and the sad truth is that we still do not have an effective treatment to cure this disease. The problem lies in the fact that we do not fully understand what causes ALS in the first place. In his doctorate, Jimmy Beckers is trying to solve a piece of the puzzle. He is investigating whether a malfunction in our internal cellular recycling system might be linked to ALS.

Once diagnosed with glioblastoma, a highly aggressive brain cancer, a patient has on average only 15 months to live. "This terrible statistic shows that we urgently need new treatment options," says Myrthe Mampay (VUB - FWO). In her research, she is looking for one such new treatment based on immunotherapy, in which she wants to use patient stem cells to make macrophages that attack the tumour.

Have you ever wondered how pills are made? A powder flows through a production line, falls into a hole, and gets compressed into a pill. Easy, right? And yet a lot can go wrong, as chemical engineer Margot Coppens explains. That's why she uses computer models to virtually test the powder mixtures and anticipate possible production problems.

When removing a kidney tumor, a surgeon has just 20 minutes to do the job. During the operation, the surgeon has to cut off the blood supply to the kidney to avoid a true blood bath. But if the kidney is without blood for too long, too much of it will die off, causing the kidney to malfunction. Using mathematical models, Saar Vermijs aims to help surgeons in their race against the clock...

Today, we can treat cancer better than ever. Yet some cancer types remain very difficult to fight. Such is the case of glioblastoma, a highly aggressive brain cancer in which only 7 in 100 patients are still alive five years after diagnosis. Hoping to help glioblastoma get small, Joke Deschildre doctored a sophisticated strategy to attack cancer cells.

Artificial feeding, such as parenteral nutrition -food that is injected directly into the bloodstream- is crucial for critically ill patients. It keeps them alive, but unfortunately, it can cause significant liver damage in the long run. To prevent liver injury, Milos Mihajlovic and his colleagues are developing an advanced human liver model in a dish to better understand how food injection leads to liver damage.

In the last decade, wildfires peaked at record numbers in different countries across the world. These fires destroy houses and burn down forests, but they also have other important 'unseen' effects. "Smoke from wildfires leads to high air pollution, which is associated with short and long-term risks, such as respiratory and cardiac diseases", as Leonidas Leiva explains. He's working on new materials to recognize, capture and neutralize these contaminants.